Patients with CF shown throughout may or may not currently be on TRIKAFTA.
Run-in with tezacaftor/ivacaftor and ivacaftor 100 mg/150 mg qd and 150 mg qd with fat-containing food
ivacaftor and ivacaftor) 200 mg/100 mg/150 mg qam and 150 mg qpm with fat-containing food (N=55)
(tezacaftor/ivacaftor and ivacaftor) 100 mg/150 mg qam and 150 mg qpm with fat-containing food (N=52)
FROM BASELINE AT WEEK 4:
Absolute Change in ppFEV1 from Baselined
Mean Absolute Change from Baseline in CFQ-R Respiratory Domain Score